Volume 21, Number 6

Table of Contents

Articles

Reducing Energy Costs in a Central Utility System through Optimization: Impact for a Pharmaceutical Company

by Eric Unrau, John Havener
This article describes how optimization software can reduce energy costs and continually improve efficiency of a central utility system.

Compliance of Pharmaceutical R&D Facilities with the Updated ASHRAE Energy Standard

by Mark Maguire
This article identifies the impact of the revised ASHRAE energy code on pharmaceutical facilities.

Improving Performance and Reducing Cycle Time Using Flow Path Management: A Case Study

by Glenn Gerecke, Tom Knight
This case study summarizes the philosophies, organizational changes, and information systems that DuPont Pharmaceutical Company and SAK Logistics implemented to achieve manufacturing excellence.

Material of Construction for Pharmaceutical and Biotechnology Processing: Moving into the 21st Century

by James Fleming, John Imbalzano, David Kemkes, David DeVoe, Lewis Crenshaw
This article compares the material of science of the current materials of construction - stainless steel and glass - with that of the increasingly adopted material - fluoropolymers, as well as the biochemical and microbiological impact on such materials.

A brief history of the GAMP forum

by Gail Evans
A brief history of the GAMP forum.

Business Considerations in Building a Computer System Validation Quality Assurance Infrastructure

by Bob Carrier
This paper presents guidance regarding considerations and approaches relevant to building a computerized systems validation infrastructure tailored to a start-up company engaging in GMP-compliant drug manufacture.

Statistical Methods for Analysis of Content Uniformity Results During Process Development

by Ed Carey, Joe Leonard, James Reilly
This article uses a series of different statistical methods to analyze content uniformity results.

Pharmaceutical Purified Water Storage and Distribution Systems - an Engineering Prospective

by Leonid Shnayder
This article describes common practices related to the design of purified water storage and distribution systems.

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