Glossary

Electric Resistance-Welded (pipe)

The red blood cell consisting largely of hemoglobin and carrying nearly all the oxygen contained in the blood. Erythrocytes are biconcave discs that are manufactured in the bone marrow.

An antibiotic that binds to the 50S subunit of prokaryotic ribosomes and inhibits translocation of mRNA along the ribosome.

Electrospray

Electronic Signatures

European Society for Animal Cell Technology

Electron Spectroscopy for Chemical Analysis

(also see: Rescue Medication)

A relatively harmless human intestinal bacterium. Laboratory strains of these bacteria have been kept for many years and are commonly used in the production of recombinant proteins.

A fast growing, Gram-negative bacteria commonly found in the body with a comparatively simple structure. The genetic make up of E. coli is the best known of any organism, having been widely studied during the development of genetic engineering. It has been used extensively as the host cell for novel proteins made by rDNA technology.

Electrostatic Discharge

Enhanced Small Device Interface

Emulsion Solvent Evaporation

Electronic Secure Mail (CBER)

Electronic Submissions Program (FDA)

Energy Star Portfolio Manager (EPA)

An amino acid that cannot be synthesized by animals and therefore has to be ingested with feed or food.

Those that satisfy the health care needs of the majority of the population. Each country may generate its own list of essential drugs.

Any of a number of elements required by living organisms to ensure normal growth, development and maintenance.

The group of polyunsaturated fatty acids of plants required in the human diet.

Expressed Sequence Tag

Submitted concurrently with the Product License Application (PLA), the ELA provides data demonstrating the acceptability of the facilities and personnel for manufacturing the protein pharmaceutical.