Glossary

(USP <1072>) A chemical or physical agent that destroys or removes vegetative forms of harmful microorganisms when applied to a surface.

Process by which viable microbiological agents or eukaryotic cells are reduced to a level unlikely to produce disease in healthy people, plants, or animals. These processes may use chemical agents, heat, ultraviolet light, etc. to destroy most (but not necessarily all) of the harmful or objectionable microorganisms, pathogens, and potential pathogens. Disinfection does not necessarily result in sterilization.1.“High level disinfection” inactivates fungi, viruses, and bacteria. High-level chemical disinfectants maybe ineffective against bacterial spores if they are present in large numbers. Extended exposure times may be required.2.“Intermediate level disinfection” destroys fungi, some viruses (lipid and most non-lipid medium-size and small viruses), mycobacteria, and bacteria.3.“Low level disinfection” kills vegetative forms of bacteria, some fungi, and some medium-size and lipid-containing viruses. Low-level disinfectants do not reliably kill bacterial spores, mycobacteria, or small or non-lipid viruses.

Removal, destruction, or de-activation of microorganisms on objects or surfaces. ISO 14644-5.

Circular rotating magnetic storage hardware. Disks can be hard (fixed) or flexible (removable) and different sizes.

Hardware used to read from or write to a disk or diskette.

An operating system program; e.g., DR-DOS from Digital Research, MS-DOS from Microsoft Corp., OS/2 from IBM, PC-DOS from IBM, System-7 from Apple.

The official name of the floppy disk. A thin, flexible plastic disk coated with magnetic material, on which data and programs can be stored for later retrieval: used mainly with microcomputers.

Management of the flow of production units in the form of jobs, orders, batches/runs, lots, and Work Orders. Dispatch Information is presented in the sequence in which the works needs to be done and changes in real time as events occur on the factory floor. It has the ability to alter the prescribed schedule on the factory floor. Rework and salvage processes are available, as well as the ability to control the amount of Work In Process at any time with buffer management.

The pouring or transferring of any material from a container, tank or similar vessel, whereby vapors, dusts, fumes, mists or gases may be liberated to the atmosphere.

Allocation and provision of IMP for subject use for home treatment or for hospital administration to subject. Refers to IMP which has been packaged in accordance with regulations and is ready for administration to the subject.

Pre-sterilized products, equipment, and packaging designed to be used once or a few times, depending on specific circumstances, and discarded. These items are sometimes referred to as “single use”.(also see: Single Use)

Pre-sterilized products, equipment, and packaging designed to be used once or a few times, depending on specific circumstances, and discarded. These items are sometimes referred to as “single use”.(also see: Single Use)

An archivists’ term: how records are handled once the retention period has been met. Disposition usually refers to deletion, but can include transfer to another agency or archive.

An OAIS term: an Information Package that is delivered by the archive to a Consumer, i.e., someone who requests and receives information from an archive. One of several Archival Information Packages constructs a DIP.

The breakdown of food material to yield energy and building blocks for cellular synthesis.

The amount of nonvolatile matter dissolved in a water sample, usually expressed in parts per million (PPM) by weight.

The process of heating a mixture to separate the more volatile from the less volatile parts, and then cooling and condensing the resulting vapor so as to produce a more nearly pure or refined substance.

The process of separating water from impurities by heating until it changes into vapor and then cooling the vapor to condense it into purified water.

A system architecture wherein database and/or processing occur on multiple servers. This is usually based on geographic considerations, but also may be load-driven.

Centralized system for the delivery of fluids from point of generation or supply to point of use.

Division of Information Technology (CDER)

Division of Information Technology (NCTR)

Term describing the occurrence of an event at least once every 24 hours.

Division of In Vitro and Biochemical Toxicology (CFSAN)