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  • DIC

    Disseminated Intravascular Coagulation
  • DIC

    Dairy Industry Committee
  • DICOM

    Digital Imaging and Communications in Medicine
  • DID (CBER)

    Division of Information Development (CBER)
  • DIDP (CBER)

    Division of Information Disclosure Policy (CDER)
  • Different Software System Analysis

    (IEEE) Analysis of the allocation of software requirements to separate computer systems to reduce integration and interface errors related to safety. Performed when more than one software system is being integrated.
  • Differential Backup

    A differential backup is a cumulative backup of all changes made after the last full backup. The advantage to this is the quicker recovery time as compared to Incremental Backup, requiring only a full backup and the latest differential backup to restore the system. The disadvantage is that for each day elapsed since the last full backup; more data needs to be backed up, specially if a majority of the data of the data has been changed.
  • Differential Centrifugation

    A method of separating sub-cellular particles according to their sedimentation coefficients, which are roughly proportional to their size. Cell extracts are subjected to a succession of centrifuge runs at progressively faster rotation speeds. Large particles, such as nuclei or mitochondria, will be precipitated at relatively slow speeds; higher G forces will be required to sediment small particles, such as ribosomes.
  • Differential Mobility Analyzer (DMA)

    Instrument for measuring the particle size distribution, based on the electrical mobility of particles.
  • Differential Pressure (DP)

    Between adjoining rooms or zones, measured in Pascals (Pa) (1 inch wg = 254 pa).
  • Differential Scanning Calorimetry (DSC)

    (ASTM A 1445) A technique in which the difference in energy inputs into a substance and a reference material is measured as a function of temperature, while the substance and the reference material are subjected to a controlled temperature program.
  • Differential Thermal Analysis (DTA)

    (ASTM A 1445) A technique in which the temperature difference between a substance and reference material is measured as a function of temperature while the substance and the reference material are subjected to a controlled temperature program.
  • Differentiation

    The process of biochemical and structural changes by which cells become specialized in form and function.
  • Diffusion

    A migration of a solute from a region of high concentration to a region of lower concentration. In most integrity tests the solute is air or nitrogen, which diffuses through a wetted membrane.
  • Diffusion

    The random thermal motion of particles, which causes them to flow from a region of higher concentration to one of lower concentration until they are uniformly distributed.
  • Diffusion Battery Element

    Individual component from a multi-stage particle size cutoff device operating on the principle of diffusion to remove smaller particles from an aerosol stream.
  • Diffusion Test

    Test based on the fact that under pressure, compressed air or nitrogen flows through the liquid that is held in the filter’s pores at differential pressures below the bubble point. In small area filters, this airflow is very slow and often not measurable. But in large area filters, it is significant enough to measure and provide a sensitive filter integrity test.
  • Digestion

    The enzymatic hydrolysis of major nutrients in the gastrointestinal system to yield their building-block components.
  • Digital

    A series of on and off pulses arranged to convey information.
  • Digital

    Pertaining to data (signals) in the form of discrete (separate/pulse form) integral values.
  • Digital Certificate

    An attachment to an electronic message used for security purposes. The most common use of a digital certificate is to verify that a user sending a message is who he or she claims to be and to provide the receiver with the means to encode a reply.
  • Digital Representation

    Biometric parameters such as a fingerprint or retinal pattern are turned into data that a computer understands: the digital representation of the biometric. The pattern in the biometric divides it into a grid of boxes, and a zero or a one, depending on whether the box is filled in, marks each box.
  • Digital Signature

    An electronic signature based upon cryptographic methods of originator authentication, computed by using a set of rules and a set of parameters such that the identity of the signer and the integrity of the data can be verified.
  • Digital-to-Analog Converter (DAC)

    Output related devices which translate a computer's digital outputs to the corresponding analog signals needed by an output device such as an actuator.
  • Digitale Unterschriften