Glossary

Biological oxygen demand of water. The oxygen required by bacteria for oxidation of the soluble organic matter under controlled test conditions.

The temperature at which a liquid boils and changes rapidly to a vapor (gas) state at a given pressure. Expressed in degrees Fahrenheit (ºF) or degrees Centigrade (ºC) at sea level pressure.

Body of Knowledge Committee (ISPE term)

Beginning-Of-Lamp-Life

A threaded fastener with a head on one end.

A Trojan horse which attacks a computer system upon the occurrence of a specific logical event (logic bomb), the occurrence of a specific time-related logical event (time bomb), or is hidden in electronic mail or data and is triggered when read in a certain way (letter bomb).

The soft blood-forming tissue that fills the cavities of bones and contains fat and immature and mature blood cells, including white blood cells, red blood cells, and platelets. Diseases or drugs that affect the bone marrow can affect the total counts of these cells.

A medical procedure to replenish the soft tissue within bones that produces new blood cells. Bone marrow transplants are necessary when marrow has been destroyed by drug or radiation therapy for cancer, often leukemia. A bone marrow donor is usually a close relative of the patient.

A combination of a label and a booklet containing multiple pages with country specific information on local language (a label with at least three pages).

Pertaining to the principles of mathematical logic developed by George Boole, a nineteenth century mathematician. Boolean algebra is the study of operations carried out on variables that can have only one of two possible values; i.e., 1 (true) and 0 (false). As ADD, SUBTRACT, MULTIPLY, and DIVIDE are the primary operations of arithmetic, AND, OR, and NOT are the primary operations of Boolean Logic. In Pascal a Boolean variable is a variable that can have one of two possible values, true or false.

To cause a computer system to reach a known beginning state. A boot program, in firmware, typically performs this function which includes loading basic instructions which tell the computer how to load programs into memory and how to begin executing those programs. A distinction can be made between a warm boot and a cold boot:Cold boot means starting the system from a powered-down state.Warm boot means restarting the computer while it is powered-up.Important differences between the two procedures are:1)A power-up self-test, in which various portions of the hardware (such as memory) are tested for proper operation, is performed during a cold boot while a warm boot does not normally perform such self-tests.2)A warm boot does not clear all memory.

(IEEE) To initialize a computer system by clearing memory and reloading the operating system.

(IEEE) A short computer program that is permanently resident or easily loaded into a computer and whose execution brings a larger program, such an operating system or its loader, into memory.

Boards of Pharmacy

Biaxially Oriented Polypropylene

A device for indirect visual inspection of difficult access locations such as equipment and pipes

Building Operations Staff (CBER)

Boston (Massachusetts) District Office (ORA)

(USP) Plant materials that claim to affect the well-being of an individual.

Estimate derived from the analysisi of specific project tasks utilizing historic comparison information, regulatory requirements, and owner policies to derive a value for each.

Project initiated by an existing site which has identified a process improvement or new technology which can improve quality, yield, cycle time reduction, improve safety or just replace old assets.

Any of several potent neurotoxins produced by botulinum and resistant to proteolytic digestion.

An anaerobic, rod-shaped bacterium (Clostridium botulinum) that secretes botulin and inhabits soils. Clostridium botulinum produces 7 distinct toxins, types A through G. Botulinum toxin type A is the most studied of the 7 serotypes produced by the anaerobic bacterium Clostridium botulinum. Minute quantities of botulinum toxin type A offer significant potential in treating a wide variety of disorders associated with muscle overactivity. Botulinum toxin type A, currently commercialized under the trade name BOTOX®.

Water held by the cell and not released if freezing occurs in the intercellular space.