Glossary

Thin-Layer Chromatography

Threshold Limit Value

An ACGIH designated degree of exposure to contaminants and expressed as parts of vapor or gas per million parts of air by volume at 25°C and 760mmHG pressure, or as approximate milligrams or particulate per cubic meter of air (mg/m³). An exposure level under which most people can work consistently for 8 hours a day, with no harmful effects. TLVs are listed as either an 8-hour TWA or a 15-minute STEL.

Traceability Matrix

Total Productive Maintenance

Tumor Necrosis Factor

Tenecplase

Tumor Necrosis Therapy

Therapeutic agents that target dead and dying cells found primarily at the core of the tumor.

Total Organic Carbon

The junction between the face of a weld and the base material.

Tolerance is the permissible deviation from a specified value.

A form of genetic resistance in which an organism attacked or affected by a disease pathogen (or pest) exhibits less reduction in yield or performance in comparison with members of other affected cultivars or breeds.

A unit used to indicate the size of a refrigeration unit. One ton of refrigeration effect is equivalent to removing 12,000 Btu/hr of heat, or melting one ton of ice in a 24-hour period.

Turnover Package

Pertaining to design methodology that starts with the highest level of abstraction and proceeds through progressively lower levels.

“Rule of Thumb” estimate based upon an overall project estimate using only one parameter to determine the value (i.e., level of required regulatory compliance, square footage, similar building type, similar systems comparison).

Project initiated by a business owner wanting a capability installed to discover or manufacture a product.

A medication applied to the skin, an ointment. Usually a medicament suspended in a carrier such as petrolatum or another oil based carrier. Filtration at elevated temperatures is usually possible.

A pharmaceutical product meant to be applied to the skin or soft tissue in the form of liquid, cream, or ointment, and therefore needs not be aseptic. Sterile ophthalmic products throughout are manufactured aseptically.

An obsolete unit of pressure equal to that exerted by a column of mercury 1mm high at 0°C and standard gravity (1mm Hg); named after Evangelista Torricelli (1608-1647), the inventor of the mercury barometer. 1 Torr = 1/760 atm = 133.322 Pa.

Air volume that passes through a section of an installation in unit of time.

An estimation of the total number of bacteria in a sample based usually on Standard Methods procedures for collecting, incubating, and counting colony-forming units (cfu).