Glossary

American Standard Code for Information Interchange (computer files)

American Society for Clinical Oncology

A family of fungi marked by long spore-containing cells. Form sexual spores called ascospores, which are contained within a sac (a capsule structure). Ergot, truffles, some molds of the genera Neurospora and Aspergillus, and yeasts belong to this category.

(C6H8O6) A water-soluble vitamin present naturally in some plants, and also synthetically produced. Aside from its role as a vitamin, it is used as an antioxidant in plant tissue culture; and included in disinfection solutions.

A spore produced within the saclike (ascus) cell of the sexual state of a fungus.

American Society for Clinical Pathology

American Society for Clinical Pharmacology and Therapeutics

Autologous Skin Cell Transplant

Atherosclerotic Cardiovascular Disease

Atrial Septal Defect

Assistant Secretary of Defense for Homeland Defense

Association of South-East Asian Nations (RHI)

A condition in which living pathogenic (causing or capable of causing disease) organisms are absent.

(PDA TR 22) Free from disease-producing microorganisms.

Not sterile, but contaminants controlled within established acceptable limits.

Processing conditions designed to achieve a sterile product.

Asepsis or sterile. The state of being free of contaminating organisms (bacteria, fungi, algae and all micro-organisms except viruses) but not necessarily free of internal symbionts.

Not sterile, but contaminants controlled within established acceptable limits.

Not sterile, but contaminants controlled within established acceptable limits.

Free of pathogenic (causing or capable of causing disease) microorganisms.

A type of closed isolator that is sealed or is supplied with air through a microbially retentive filtration system (HEPA minimum) and is able to be reproducibly decontaminated. When closed it uses only decontaminated interfaces or Rapid Transfer Ports (RTPs) for material transfer. When open it allows the egress of materials through a defined opening that has been designed and validated to preclude the entry of contamination.

Operating in a manner that prevents contamination of the process.

(PDA TR 22) Handling sterile materials in a controlled environment, in which the air supply, materials, equipment, and personnel are regulated to control microbial and particulate contamination to acceptable levels.

Area in which sterile product is formulated, filled into containers, and sealed.

The transfer of material from a vessel or process to another vessel or process without introduction of contamination from outside the process.