Stacy L. Springs

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MIT Center for Biomedical Innovation
Biomanufacturing Program Director
Stacy L. Springs is the Senior Director of Programs at that Massachusetts Institute of Technology (MIT) Center for Biomedical Innovation and the Executive Director of Biomanufacturing Initiatives, including MIT’s Biomanufacturing Program, its Consortia on Adventitious Agent Contamination in Biomanufacturing, and the BioACCESS initiative. Stacy also serves as the Executive Director for the Sloan School’s Food Supply Chain Analytics and Sensing Initiative. She holds a PhD in chemistry from the University of Texas at Austin and gained postdoctoral training in protein and biophysical chemistry at Princeton University. Stacy has been an ISPE member since 2009.

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Effect of Industry 4.0 enablers on the product life cycle.
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Data Science for Pharma 4.0™: Drug Development, & Production—Part 2

This second of a two-part series explores digital transformation and digitalization in the biopharmaceutical industry with information about how data science enables digitalization along the product life cycle. (Part 1 was published in the March-April 2021 issue of Pharmaceutical Engineering.1

  • 1Herwig, C., et al. “Data Science for Pharma 4.0™, Drug Development, and Production—Part...
Effect of Indutry 4.0 enablers on the manufacturing process chain. Upper arrow: Conventional approach. Lower arrow: Perceived extended process chain using IIoT enablers.
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Data Science for Pharma 4.0™, Drug Development, & Production—Part 1

Digital transformation and digitalization are on the agenda for all organizations in the biopharmaceutical industry. But what are the main enablers of intelligent manufacturing? We hypothesize that data science–derived manufacturing process and product understanding is the main driver of digitalization in the bioprocessing industry for biologics manufacturing. In this article, the first of a...