Eric Karl Zimmerer

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Engineer I in the Biocontinuum Group
Eric Karl Zimmerer is an Engineer I in the biocontinuum group at MilliporeSigma. He is an early career scientist and received a BS in chemical engineering from the Pennsylvania State University. Since joining the biocontinuum group, he has assisted in the development of lab-scale systems for continuous bioprocessing and application of digital technologies to continuous bioprocessing.

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Figure 1: Batch manufacturing process vs. a low pH iVI process.
Technical
Continuous Process: Implementing Low pH Viral Inactivation in a Continuous Process

Viral inactivation (VI) is a critical step in ensuring the safety of monoclonal antibody (mAb), Fc fusion, and recombinant protein therapeutics and it is typically an important component of an overall virus control strategy for downstream biotherapeutic production processes. Considerations for successful implementation of an inline VI process are discussed in this article.