Glossary

Systems or processes that have demonstrated functional capability and regulatory acceptance over several years of usage. In many cases, these may be common practice with the industry

A cogeneration system that simultaneously produces mechanical power (often converted to electricity), heat, and cooling from a single heat source such as fuel or solar energy.

Compounds present in the feed water that are formed by the reaction of chlorine and the organic material in the water. The most common THM found in water is chloroform, which is quite difficult to remove. Activated carbon and degasification can reduce THMs.

A process in which conjugation is used to transfer a plasmid vector to a target cell when the plasmid vector is not self-mobilizable. When (1) cells that have a plasmid with conjugative and mobilizing functions are mixed with (2) cells that carry the plasmid vector and (3) target cells, mobilizing plasmids enter the cells with the plasmid vector and mobilize the plasmid vector to enter into the target cells. Following tripartite mating, the target cells with the plasmid vector are separated from the other cell types in the mixture by various selection procedures.

Possessing three copies of a particular chromosome instead of the normal two copies.

A method of attacking a computer system, typically by providing a useful program which contains code intended to compromise a computer system by secretly providing for unauthorized access, the unauthorized collection of privileged system or user data, the unauthorized reading or altering of files, the performance of unintended and unexpected functions, or the malicious destruction of software and hardware.

An involuntary plant response to a stimulus, in which a bending, turning or growth occurs, such as phototropism, geotropism or hydrotropism. The response may be positive (towards) or negative (away from) to the stimulus.

One of over 20 naturally occurring amino acids.

(ICH Q2 (R1))

For a record to remain reliable, authentic, with its integrity maintained, and useable for as long as the record is needed, it is necessary to preserve its content, context, meaning, and sometimes its structure.A trustworthy record preserves the actual content of the record itself and information about the record that relates to the context in which it was created and used. Specific contextual information will vary depending upon the business, legal, and regulatory requirements of the business activity. The record’s reliability and authenticity may be impaired if its structure or arrangements are not preserved. The acronym ALCOA is used to summarize the key properties of a trustworthy record.

For a record to remain reliable, authentic, with its integrity maintained, and useable for as long as the record is needed, it is necessary to preserve its content, context, meaning, and sometimes its structure.A trustworthy record preserves the actual content of the record itself and information about the record that relates to the context in which it was created and used. Specific contextual information will vary depending upon the business, legal, and regulatory requirements of the business activity. The record’s reliability and authenticity may be impaired if its structure or arrangements are not preserved. The acronym ALCOA is used to summarize the key properties of a trustworthy record.

A table that describes a logic function by listing all possible combinations of input values, and indicating, for each combination, the output value.

(ISO) An operation table for a logic operation.

Protein-splitting enzyme derived from trypsinogen in the pancreatic juice. Used to remove adherent cells from a surface and to break up (digest) purified proteins for analysis.

Trypsin allows the growth of cells as independent microorganisms distinct from tissue culture by causing cell disaggregation. Excised tissue is softened and treated with a proteolytic enzyme, normally trypsin, then washed and suspended in a growth medium to produce a primary culture. Subculturing from the primary culture usually involves treatment with antitrypsin (such as serum) to produce a secondary culture. Cell lines are established by repeated culture through cycles of growth, trypsinization, and subculture. Trypsin is also used to remove anchorage-dependent cells from their attached substratum.

Quantitating the resultant fragments caused by tryptic digestion.

Tumor Surface Antigen

Telecommunication Systems Bulletin

Toxic Substances Control Act (EPA Regulations)

Transmissible Spongiform Encephalopathy

A type of brain disease generally believed to be caused by prions.

Chronic degenerative nervous diseases characterized by the accumulation of an abnormal isoform of a cellular glycoprotein known as PrP or prion protein. TSE diseases in animals include: bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep and goats, chronic wasting disease CWD) in cervids (deer and elk), transmissible mink encephalopathy (TME) in farmed mink, feline spongiform encephalopathy (FSE) in felidae (domestic cats and captive large cats), and spongiform encephalopathy of exotic ungulates in zoos.In humans, spongiform encephalopathies include different forms of Creutzfeldt-Jakob Disease (CJD), kuru, Gertsmann-Straussler Syndrome (GSS) and fatal familial insommnia (FFI).

Thermoset Polyurethane

Total Suspended Solids