Plinio A. De los Santos is a Principal Scientist at the Center for Mathematical Science in the Merck Manufacturing Division at Merck & Co., Inc., Kenilworth, New Jersey, US. He provides statistical and mathematical support to development, manufacturing, packaging, laboratory, and supply operations of small-molecule products. His interest areas include process validation, design of experiments, statistical process control, and manufacturing systems optimization. Plinio holds a doctorate in decision sciences and engineering systems and a MS in industrial management and engineering, both from Rensselaer Polytechnic Institute, an MBA from the University of Puerto Rico, and a BS in industrial engineering from the Technological Institute of Santo Domingo.