Glossary

American Medical Association Drug Evaluations

The normal surrounding environmental conditions such as temperature, relative humidity, or room pressure of a particular area under consideration.

Air temperature at a given time and place; not radiant temperature.

Air Movement and Control Association (International)

Age-Related Macular Degeneration

Analytical Method Development

Analytical Method Development Report

Animal Medicinal Drug Use Clarification Act

Absorption, Metabolism, Excretion

Individuals have the right to amend protected health information (PHI) in the designated record set. This does not include research notes outside of the designated record set (information that would not be used for clinical or billing decisions).

An organization that coordinates the development of U.S. voluntary national standards for nearly all industries. It is the U.S. member body to ISO and IEC. Information technology standards pertain to programming languages, electronic data interchange, telecommunications and physical properties of diskettes, cartridges and magnetic tapes.

A seven-bit code adopted as a standard to represent specific data characters in computer systems, and to facilitate interchange of data between various machines and systems. Provides 128 possible characters, the first 32 of which are used for printing and transmission control. Since common storage is an 8-bit byte (256 possible characters) and ASCII uses only 128, the extra bit is used to hold a parity bit or create special symbols.

A simple bacterial test for carcinogens.

American Foundation for AIDS Research

Arzeneimittelgesetz (West Germany drug law)

Association of Minority Health Professionals Schools

Acute Myocardial Infarction

A substance that may be derived from ammonia by the replacement of one or more of the hydrogen atoms by hydrocarbon radicals.

Hydrolysis of a protein or peptide into its individual residues (free amino acids), followed by chromatographic separation and UV-vis detection for analytical purposes.

Any of a group of twenty hydrocarbon molecules (containing the radical group NH2) linked together in various combinations to form proteins in living things. Synthesized by living cells or obtained as essential components of the diet of human and animals, these twenty (20) amino acids are divided into four (4) groups on the basis of their side-chain properties:1.Neutral, hydrophobic side chains,2.Neutral, hydrophilic side chains,3.Acid, hydrophilic side chains,4.Basic, hydrophilic side chains.In addition to the twenty common amino acids there are less common derivatives (e.g. hydroxyproline, found in collagen) formed by the modification of a common amino acid.

Any of 20 basic building blocks of proteins with a free amino (NH2) and a free carboxyl (COOH) group, and having the basic formula NH2 – CR – COOH.According to the side group R, they are subdivided into:Polar or Hydrophilic1 serine (alpha-amino-beta-hydroxypropionic acid)2 threonine (alpha-amino beta-hydroxy butyric acid)3 tyrosine (alpha-amino-beta-(p-hydroxyphenyl) propionic acid)4 asparagine5 glutamineNonpolar or Hydrophobic6 alanine (aminopropionic acid)7 glycine (aminoacetic acid)8 valine (alpha-amino-isovalerianic acid)9 leucine (alpha-amino-isobutylacetic acid)10 isoleucine11 proline (pyrrolidine-alpha-carboxylic acid)12 phenylalanine (phenylaminopropionic acid)13 tryptophan (alpha-amino-beta-indole-propionic acid)14 cysteine (alpha-amino-beta-thiopropionic acid)15 methionine (gamma-methylthio-alpha-amino butyric acid)Acidic16 aspartic acid17 glutamic acidBasics18 lysine19 histidine 20 arginine (alpha-amino-delta-guanidino-valerie acid)The sequence of amino acids determines the shape, properties and the biological role of a protein. Plants and many micro-organisms can synthesize amino acids from simple inorganic compounds, but animals are unable to synthesize some of them, called essential amino acids, so they must be present in the diet.

The –NH2 group. Amino groups are weakly basic and are found in organic molecules. Important for biochemists to bind and sequence peptides.

The N-terminus region of a polypeptide. The amino terminus end of a polypeptide contains the free amino group.

Acute Myelogenous Leukemia

Acute Myeloid Leukemia