Re-imagine Chromatography
4 Dec 2024 | 13:00-17:15 SGT
Sartorius Office & Application Center
30 Pasir Panjang Rd, #06-31A/32, Singapore 117440
Places are limited and subject to approval; confirmations will be sent via kristina.autenrieth@ispesingapore.org.
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Presentation Topic 1
Intensify your process with Multi-Column and Membrane/Resin Chromatography : process development, digital tools and implementation at commercial scale.
Abstract :
Multi-Column or Multi Membranes/Resin in Sartorius’s portfolio will be presented with case studies at PD scale and commercial scale. Digital tools used for process optimization and process monitoring/control will also be introduced during this session.
Key objective :
Inform about the development stage of process intensification at small and large scale, and discuss methodologies to convert a batch process to an intensified process through multi-columns/membranes approach.
Presentation Topic 2
Transforming art into science – Automated Column Packing
Abstract:
Full automation is the only way forward for large-scale packed bed chromatography, but not all automated systems deliver the same levels of performance. Resolute® Linear columns with the AutoPak system deliver fully automated packing, repacking, unpacking and clean-in-place (CIP) operations, which greatly reduces operator error and allows for robust, predictable processing.
Key Objective:
- Understand why automated column packing is superior to manual packing.
- Understand the benefits of automation and why automation should be considered independently for packing, unpacking, repacking and CIP.
- Learn from our chromatography expert and understand how truly optimized automation solutions combine expertise with technology.
Workshop Leaders
Verena Tan, Product Specialist, Chromatography Systems, Sartorius
Verena works as a product specialist at Sartorius and is an expert on formulating commercial strategies. With more than 10 years of experience on downstream processes in the biopharmaceutical industry, Verena provides technical support for the chromatography hardware portfolio. Before joining Sartorius, Verena was part of the MSAT DSP team where she worked on technology transfer and process optimization projects. Verena holds a master’s degree in industrial systems engineering and a bachelor’s degree in chemical engineering from the National University of Singapore.
Yvan Ruland, Technology Consulting Chromatography, Sartorius
Yvan specializes in the purification of active substances by preparative chromatography in the Pharmaceutical, Biopharmaceutical and Food industries.
He holds a PhD in organic chemistry applied to biomolecules and has over 20 years of experience in the fields of equipment supply and process development for batch and multi column chromatography, for clinical or commercial scale production.
Yvan has focused on process intensification through Multi Column Chromatography (mAb’s, Plasma, chiral separations, natural extracts) and on modalities requiring HPLC technologies (Tides, GLP-1 receptor agonists, Insulin and analogs, small molecules).
Over his career, he has held different positions in Process Development and Technology Consulting in France, USA and China and he is currently based in Singapore providing his expertise within Sartorius since its recent acquisition of Novasep Equipment’s division.
Yudhi Li, Sales Development Specialist, Chromatography, Sartorius
Yudhi Li is a chromatography specialist from Sartorius. He received his M. Sc in Chemical Engineering from National University in Singapore. He had experience with large Biotechs before joining Sartorius in 2020. His past experiences includes scaling up membrane and multi column chromatography processes.