A Transformational Air Purification Technology and Paradigm Shift in Healthcare and Life Sciences

VOCs are common airborne constituents of outside source air, recirculated laboratory air, HVAC components, tissue cultureware, and cell culture procedures. VOCs play a critical role in cell arrest, delay and mortality. Research has demonstrated that a large range of VOCs exist within biopharmaceutical processing facilities and cause cytotoxicity by perturbing cellular membranes, increasing intracellular calcium ions, impairing mitochondrial function, increasing DNA oxidative damage, increasing DNA fragmentation, and interfering with DNA and RNA replication processes. Case studies will be presented to show that volatile organic compounds (VOCs) and low levels of viable particulates, bacterial and viral, have detrimental effects on cell viability and growth.

Significant research has defined the airborne metrics critical in the consistent support of the cultured living cell and that it is critical to drive airborne VOCs and viable particulates to below detection. Within life sciences, the LifeAire System has been proven to improve cell growth and viability and will positively impact cell culture success rates, increasing the number of successful deliveries of a cellular product to the patient. This air purification technology is a process that will help to achieve and maintain the highest level of air purity essential to clean room and cell and gene therapy labs areas. Getting to these levels involves addressing issues across an array of areas: cytotoxic airborne pollutants, operating environments, SOPs, building and construction materials, etc.

Learning objectives:

  1. Establish the criticality of air purification technology in improving cell growth and viability for successful cell culture processes.
  2. Understand the factors involved in selecting effective air purification equipment for certain conditions or applications.
  3. Review the detrimental effects of volatile organic compounds (VOCs) and viable particulates using case studies.
  4. Introduction to airborne metrics developed to drive VOCs and viable particulates to levels below detection.
  5. COVID Specific: Discuss the most current data specific to the mechanisms, timing and common activities underlying our exposure to COVID-19 and similar viruses – airborne and surface transmission.

Who should attend:

  1. Bioengineers
  2. Biologists
  3. Cell physiologists
  4. HVAC engineers
  5. Project engineers

Event Sponsor:

HSC Builders & Construction Managers

HSC Builders & Construction Managers


Kathryn Colonna Worrilow

Dr. Kathryn Colonna Worrilow

Dr. Kathryn Colonna Worrilow received her bachelor’s degree in Biology and Mathematics at Randolph Macon Women’s College. She received her Ph.D. in Anatomy and Cell Physiology from the University of Virginia School of Medicine and went on to pursue her post-doctoral fellowship in Reproductive Physiology and Infertility at the University of Pennsylvania School of Medicine.

Dr. Worrilow was the Scientific Director of In Vitro Fertilization and Andrology Laboratories for over 20 years, served as an Adjunct Professor at The Pennsylvania State University Lehigh Valley, and as the CEO of LifeAire Systems, LLC for the past 9 and a half years.

Working with a team of chemists, engineers, and physicists, Dr. Worrilow developed the LifeAire System. Its proprietary, staged, and patented technology comprehensively addresses airborne chemical and biological pathogens. It is quite simply, the most powerful defense a laboratory or cleanroom can employ, and your fastest path to a significant improvement in outcomes.

Registration Information:



ISPE Members




Young Professional/Student


Group/Multiple Participants (in one sitting) $50

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