Processes along the value chain – R&D, production, fill & finish – rely on aseptic environments designated by zones to protect product from environmental influence. Operators often rely on hydrogen peroxide for bio-decontamination of airlocks, transfer hatches, isolators and (c)RABS, which depending on the environment can happen as often as daily or as infrequently as once a year.
For validation of the decontamination cycle, bio-markers and equipment to detect parameters such as temperature, H2O2 concentration and humidity are employed. This ensures the decontamination process runs within spec and thus the ensuing production process is capable to deliver robust output. The introduction of probes and sensors for bio-decontamination process control does bring new challenges though, e.g. how to make sure that the equipment is calibrated correctly in a highly regulated environment.
This webinar will look at challenges in H2O2 bio-decontamination, take a deeper look into equipment to control this process, and review how to overcome challenges to handle & calibrate process control equipment in cleanroom conditions – with the ultimate goal to reduce idle time and increase product throughput.
*ISPE Membership is required for these registration rates.
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