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Sponsored Content

TOC Analysis for Cleaning Validation

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Total Organic Carbon (TOC) analysis is a fast and straightforward analytical method that effectively detects all organic residues—including active pharmaceutical ingredients, cleaning agents, degradants, and excipients—while requiring simpler method development and delivering quicker results compared to targeted techniques like HPLC. TOC offers flexible deployment options, functioning as either a laboratory-based analysis or as integrated process analytical technology (PAT) that can be positioned at-line or continuously online within clean-in- place (CIP) systems to monitor your cleaning processes in real time. By understanding how different TOC deployment approaches align with your validation strategy, sampling needs, and automation requirements, you can select the solution that best supports your operational goals while improving equipment performance, reducing contamination risks, and enhancing overall quality control efficiency.


Veolia

Veolia designs and manufactures Sievers Analytical Instruments that enable reporting of organic carbon levels and other contaminants in water, specializing in total organic carbon, bacterial endotoxins, and rapid bioburden testing. Our analyzers provide stable, accurate, near real-time data for treatment optimization, quality control and regulatory compliance in industrial, environmental and life sciences industries including pharmaceutical, drinking water, chemical processing, semiconductor and more, allowing customers to optimize their resource management and strengthen their environmental and economic performance. In short, we make complex measurements simple. 

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