White Paper — Sponsored Content

Scalable, Real-Time Bioprocess Monitoring Solution

Maryann Cuellar
Scalable, Real-Time Bioprocess Monitoring Solution

Kaiser Raman technology and Sartorius BioPAT® Spectro yield value from early process development to single-use manufacturing

Raman spectroscopy is used in biomanufacturing as a process analytical technology (PAT) tool, enabling rapid, non-destructive, in-process measurements. However, Raman data collection at early stages of bioprocess development has been a challenge since there was no interface to bioreactors less than 250 mL. Realizing the industry was struggling to capitalize on the full potential of Raman spectroscopy, Kaiser Optical Systems, Inc. (Kaiser), an Endress+Hauser company, collaborated with Sartorius to bring Raman to Ambr® 15 micro-bioreactors (10-15 mL) and Ambr 250 minibioreactors (100-250 mL). Sartorius’s new BioPAT Spectro platform enables Kaiser Raman-based Quality by Design (QbD) early on in process development and scales up to Biostat STR® single-use bioreactors.

This Q&A explains how Kaiser Raman technology and the BioPAT Spectro platform by Sartorius work together to provide biopharma manufacturers with scalable, real-time bioprocessing monitoring.

Endress+Hauser LogoEndress+Hauser is a global leader in measurement instrumentation, services and solutions for industrial process engineering. We provide process solutions for flow, level, pressure, analytics, temperature, recording and digital communications, optimizing processes in terms of economic efficiency, safety & environmental impact. Our customers come from various industries, including chemical, food & beverage, life sciences, power & energy, mining, minerals & metals, oil & gas and water & wastewater.

Kaiser Optical Systems, Inc. (Kaiser), an Endress+Hauser company, is the global leader in Raman spectroscopic instrumentation for optical composition analysis in laboratory, process, and manufacturing environments. A trusted partner in Raman for over 30 years, Kaiser Raman technology is used throughout the chemical, food and beverage, oil and gas, pharmaceutical, and biopharmaceutical industries to optimize process efficiency and ensure quality.

Download White Paper


To download this white paper, complete the form below. Once submitted, you will receive a link via the email you provided to download the white paper.

Name
Company Type
Address

By completing this form, you consent to have your information provided to the third-party sponsor of this content and may use your information to provide information about relevant products, services, and other opportunities which may be of interest to you . ISPE will store your information in a secure environment and may use your information to provide information about relevant products, services, and other opportunities which may be of interest to you. You may unsubscribe from these ISPE communications at any time. For more information or to unsubscribe, review our Privacy Policy or contact us at ask@ispe.org.