InTouch
November / December 2025

Volunteer Profile: Stephanie Stärkle Sustainability Community of Practice Co-Chair

Marcy Sanford
Volunteer Profile: Stephanie Stärkle

Stephanie Stärkle is a project engineer at VTU Engineering in Switzerland, where she leads engineering projects from concept to execution in GMP-regulated environments including cost estimation, equipment design and specification, deadline management, and coordination with cross-functional stakeholders such as vendors, quality assurance, operations, and qualification. She holds a bachelor’s degree in biotechnology and a master’s degree in applied biosciences. In addition to co-chairing the Sustainability Community of Practice (CoP), Stephanie is a member the ISPE Germany, Austria, Switzerland (D/A/CH) Affiliate’s Women in Pharma® Steering Committee and ISPE D/A/CH Emerging Leaders.

What Drew You to a Career in the Life Sciences Industry?

My interest in pharma started in high school biology and chemistry, where I learned how molecular interactions—like enzymes binding to substrates or antibodies targeting pathogens—could translate into real treatments. That’s what drew me to biotechnology and pharma: I wanted to work at the intersection of discovery and impact, where you take those precise mechanisms and turn them into therapies that change lives. Ultimately, this interest led me to engineering—where we design and scale up production facilities that enable the manufacture of these complex biologics at industrial scale.

What Do You Enjoy Most About Your Work?

What I enjoy most is being part of the entire project life cycle—from initial design to final implementation. It’s incredibly rewarding to see an idea evolve on paper into a fully functional solution. Working closely with different teams to overcome challenges and hit milestones creates a real sense of shared accomplishment. And because every project involves new people, new challenges, and new solutions, no two days are ever the same.

How Do You See Sustainability Shaping the Industry?

I see the growing need for sustainability to be more deeply integrated. This means making greener procurement choices, preparing our operations for evolving regulations, and gaining a clearer understanding of the carbon impact of our systems. We’re realizing that meaningful progress requires moving beyond surface-level criteria and labels, which in some cases has led to a loss of trust due to perceptions of greenwashing. For engineering teams, it’s about designing systems that holistically optimize resource use, energy efficiency, and material flows—creating facilities that deliver both operational and environmental performance through fundamentally sustainable design principles.

This includes rethinking traditionally high-impact areas. One key example is HVAC systems, which are prime targets for sustainability efforts, as they typically account for 50% to 80% of energy consumption in a clean manufacturing facility. This high energy use stems from the stringent requirements to maintain the controlled environments—temperature, humidity, and air quality—that are critical for meeting pharmaceutical production and storage standards.

Assumptions around cleanroom HVAC have led many to believe there are no viable alternatives to reduce this waste. Therefore, it is essential that engineering teams, sustainability experts, operations, and regulators collaborate—while also leveraging emerging technologies and Pharma 4.0™ initiatives—to design more sustainable HVAC systems. Such systems can deliver significant reductions in total operating costs while maintaining compliance and high performance.

What Do You Enjoy About Being a Member of the CoP?

Volunteering with ISPE has given me the chance to co-chair the Sustainability CoP and support the sustainability sessions for the 2025 ISPE Annual Meeting & Expo. It’s been a great way to stay close to new regulations and see what companies are actually doing to become more sustainable while also learning about the challenges they face. I appreciate being part of a community that’s working together to make steady progress toward more sustainable practices in the industry.

Join a Communities of Practice

Are you an ISPE Member looking for a better way to connect with your colleagues from around the globe? Or are you a Member seeking information on new trends, issues or concerns affecting your profession and your day-to-day work life?  Join an ISPE Community of Practice (CoP). CoPs are groups of ISPE Members with a common interest and similar job functions who collaborate on topic-specific discussions using the ISPE networking forum, ISPE Engage.