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At-Line TOC Reduces Costs by 92% for Pharmaceutical Manufacturer

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A leading BioPharma manufacturer specializing in life-sustaining proteins faced challenges with cleaning validation in its advanced production facility. To reduce costs, the company replaced a specific HPLC method with a more cost-effective Total Organic Carbon (TOC) method for routine cleaning verification and product changeovers. During a four-week pilot study, they found that their current lab-based cleaning protocol would add approximately $54,000 to costs, potentially exceeding $500,000 if continued without changes.


Veolia

Veolia designs and manufactures Sievers Analytical Instruments that enable reporting of organic carbon levels and other contaminants in water, specializing in total organic carbon, bacterial endotoxins, and rapid bioburden testing. Our analyzers provide stable, accurate, near real-time data for treatment optimization, quality control and regulatory compliance in industrial, environmental and life sciences industries including pharmaceutical, drinking water, chemical processing, semiconductor and more, allowing customers to optimize their resource management and strengthen their environmental and economic performance. In short, we make complex measurements simple.

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