At-Line TOC Reduces Costs by 92% for Pharmaceutical Manufacturer
A leading BioPharma manufacturer specializing in life-sustaining proteins faced challenges with cleaning validation in its advanced production facility. To reduce costs, the company replaced a specific HPLC method with a more cost-effective Total Organic Carbon (TOC) method for routine cleaning verification and product changeovers. During a four-week pilot study, they found that their current lab-based cleaning protocol would add approximately $54,000 to costs, potentially exceeding $500,000 if continued without changes.
