2012 Facility of the Year Awards Program Names Merck Overall Winner
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Danielle Hould
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www.ISPE.org
2012 Facility of the Year Awards Program Names
Merck’s Vaccine Bulk Manufacturing Facility (VBF)
Program of Projects as Overall Winner
(TAMPA, FLORIDA, USA, 12 November 2012) – ISPE announced during the
Plenary Session at its 2012 Annual Meeting in San Francisco, Calif. USA, that Merck’s Vaccine Bulk
Manufacturing Facility (VBF) Program of Projects is the Overall Winner of the 2012 Facility of the Year
Awards (FOYA) program.
Faced with a projected production shortfall for the Varicella product franchise, Merck responded by
delivering the Vaccine Bulk Manufacturing Facility (VBF) Program of Projects in Durham, North Carolina, USA.
The 214,000-square-foot facility was built in record time and doubled the output of the vaccine used for
Chicken Pox and Shingles.
The Merck Team used an innovative hybrid modular construction strategy that maximized off-site fabrication
and equipment testing. Interesting for this application, the integrated construction execution strategy
decoupled the design and construction of the building envelope and shell from interior process components,
enabling parallel processes – as soon as the building shell was dried in and elevated slab poured, modules
were installed simultaneously above the slab. This resulted in the ability to establish two independent work
zones (above and below the slab) and saved five months on the schedule.
The team was organized as “One Team” with all members co-located in an integrated partnership. LEAN Six
Sigma principles were used throughout the project and resulted in an accelerated transfer of systems to
operations. Integrating more than 200 lessons learned from the existing facility and process, the facility
was delivered 40% faster than industry benchmarks. For this, Merck was named the 2012 Facility of the Year
Awards Overall Winner.
More information about Merck’s winning project, as well as the Facility of the Year Awards program in
general, can be found at www.FacilityoftheYear.org.
About the Facility of the Year Awards Program
Sponsored by ISPE, INTERPHEX, and Pharmaceutical Processing magazine, the Facility of the Year Awards (FOYA) program recognizes
state-of-the-art pharmaceutical manufacturing projects that utilize new and innovative technologies to
enhance the delivery of a quality project, as well as reduce the cost of producing high-quality medicines.
Now in its seventh year, the awards program effectively spotlights the accomplishments, shared commitment,
and dedication of individuals in companies worldwide to innovate and advance pharmaceutical manufacturing
technology for the benefit of all global consumers.
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