Without a construction manager-led collaborative effort, experienced subcontractors in the life sciences market will often collaborate voluntarily among themselves after the project has started. Though voluntary collaboration tends to be prevalent, it can have a negative impact on projects if the contractor is not experienced in the market. In cases where experience is less of a priority to a customer than cost, projects may suffer from longer timelines, higher costs due to extensions, and end products (facilities) that are not able to meet regulations. The best project results come from a collaborative program led by a construction manager that fosters early engagement of all participants, allowing feedback and input in the planning phase. This approach optimizes efficiencies in the construction phase and ensures that the project is executed in a controlled and positive manner.