ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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The transplantation of tissue from one species to another species, typically from non-human mammals to humans. This technology has become very important because of a worldwide shortage of human organs for humans requiring a new organ. The most popular non-human species involved in this technology is the pig.

Publication Source: Food and Agricultural Organization of the United Nations (FAO)
Publication Date: 1999


Refers to any procedure that involves the transplantation, implantation, or infusion into a human recipient of either, (a) live cells, tissues, or organs from a nonhuman animal source, or (b) human body fluids, cells, tissues or organs that have had ex vivo contact with live nonhuman animal cells, tissues, or organs. Xenotransplantation products include live cells, tissues, or organs used in xenotransplantation.

Publication Source: ISPE Good Practice Guide: Development of Investigational Therapeutic Biological Products

Publication Date: 2007

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