ISPE Glossary of Pharmaceutical and Biotechnology Terminology

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LAL (Limulus Amoebocyte Lysate)

A material obtained by rupturing the cellular components of the blood of a horseshoe crab (Limulus Poliphemus). This material coagulates in the presence of LPS (lypopolysaccharides) and is a test used to quantitate bacterial endotoxins (pyrogens).

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